Satyam, AbhigyanKumar, PramodFan, XingliangGorelov, AlexanderRochev, YuryJoshi, LokeshPeinado, HéctorLyden, DavidThomas, BenjaminRodriguez, BrianRaghunath, MichaelPandit, AbhayZeugolis, Dimitrios2024-02-052024-02-052014-05-21Adv Mater. 2014 ;26(19):3024-34.http://hdl.handle.net/20.500.12105/17472MMC, the addition of inert polydispersed macromolecules in the culture media, effectively emulates the dense in vivo extracellular space, resulting in amplified deposition of ECM in vitro and subsequent production of cohesive, ECM-rich living substitutes.engSMURhttp://creativecommons.org/licenses/by-nc-nd/4.0/Regenerative MedicineTissue EngineeringAcrylic ResinsCell LineCollagenDextran SulfateExtracellular MatrixFibroblastsHumansMacromolecular SubstancesMatrix Metalloproteinase 2Macromolecular crowding meets tissue engineering by self-assembly: a paradigm shift in regenerative medicine.Attribution-NonCommercial-NoDerivatives 4.0 Internacional245050252619302410.1002/adma.2013044281521-4095Advanced materials (Deerfield Beach, Fla.)open access