Ferrandiz-Avellano, Maria-JoseArdanuy, CarmenLiñares, JosefinaBalsalobre-Arenas, Maria LuzGarcia, Maria Teresade la Campa, Adela G2019-11-262019-11-262011-01Antimicrob Agents Chemother. 2011 Jan;55(1):368-72. doi: 10.1128/AAC.00856-10. Epub 2010 Nov 1.0066-4804http://hdl.handle.net/20.500.12105/8709Eight rifampin-resistant streptococci of the mitis group were identified at the species level by using a concatenated 16S rRNA gene-sodA-rpoB-hlpA sequence. Characterization of their rpoB alleles showed single amino acid changes involved in rifampin resistance. Comparison of RpoB sequences from pneumococcal recombinant isolates, viridans isolates, and type strains revealed a species-specific amino acid signature, which allowed it to be ascertained that recombinant RpoBs were originated in genetic interchanges with Streptococcus mitis and Streptococcus oralis.engAMhttp://creativecommons.org/licenses/by-nc-sa/4.0/Anti-Bacterial AgentsDrug Resistance, BacterialPhylogenyRNA, Ribosomal, 16SRifampinStreptococcus mitisStreptococcus oralisStreptococcus pneumoniaeNew species genetic approach to identify strains of mitis group streptococci that are donors of rifampin resistance to Streptococcus pneumoniaeAtribución-NoComercial-CompartirIgual 4.0 Internacional21041504551368-7210.1128/AAC.00856-101098-6596Antimicrobial agents and chemotherapyopen access