Mejia-Lancheros, CiliaEstruch, RamonAngel Martinez-Gonzalez, MiguelSalas-Salvado, JordiCorella, DoloresGomez-Gracia, EnriqueFiol Sala, MiquelManuel Santos, JoseFito, MontserratAros, FernandoSerra-Majem, LluisPinto, XavierBasora, JosepVicente Sorli, JoseMunoz, Miguel-AngelPREDIMED Study Investigators2024-07-032024-07-032014-08-26Mejia-Lancheros C, Estruch R, Martinez-Gonzalez MA, Salas-Salvado J, Corella D, Gomez-Gracia E, et al. Blood pressure values and depression in hypertensive individuals at high cardiovascular risk. BMC Cardiovasc Disord. 2014 Aug 26;14:109.1471-2261http://hdl.handle.net/20.500.13003/11159http://hdl.handle.net/20.500.12105/20008Background: Hypertension and depression are both important risk factors for cardiovascular diseases. Nevertheless, the association of blood pressure on and depression has not been completely established. This study aims to analyze whether depression may influence the control of blood pressure in hypertensive individuals at high cardiovascular risk. Methods: Cross-sectional study, embedded within the PREDIMED clinical trial, of 5954 hypertensive patients with high cardiovascular risk factor profiles. The relationship between blood pressure control and depression was analyzed. A multivariate analysis (logistic and log-linear regression), adjusting for potential confounders (socio-demographic factors, body mass index, lifestyle, diabetes, dyslipidemia, and antihypertensive treatment), was performed. Results: Depressive patients, with and without antidepressant treatment, had better blood pressure control (OR: 1.28, CI 95%: 1.06-1.55, and OR: 1.30, CI 95%: 1.03-1.65, respectively) than non-depressive ones. Regarding blood pressure levels, systolic blood pressure values (mmHg) were found to be lower in both treated and untreated depressive patients (Log coefficient Beta: -1.59, 95% CI: -0.50 to -2.69 and Log coefficient Beta: -3.49, 95% CI: -2.10 to -4.87, respectively). Conclusions: Among hypertensive patients at high cardiovascular risk, the control of blood pressure was better in those diagnosed with depression.enghttp://creativecommons.org/licenses/by/4.0/HypertensionDepressionBlood pressureresearch articleAttribution 4.0 International251605631410910.1186/1471-2261-14-109BMC Cardiovascular Disordersopen accessModelos LinealesAntihipertensivosResultado del TratamientoAntidepresivosModelos LogísticosOportunidad RelativaDistribución de Chi-CuadradoAnálisis MultivarianteMasculinoHipertensiónEstudios TransversalesFactores de RiesgoPresión SanguíneaHumanosPersona de Mediana EdadDepresiónAncianoAnciano de 80 o más Años2-s2.0-84906836736341033100001L600015933