Ruiz-de-León, María JJimenez-Sousa, Maria AngelesMoreno, SantiagoGarcía, MarcialGutiirrez-Rivas, MonicaLeón, AgatheMontero-Alonso, MartaGonzález-García, JuanResino, SalvadorRallón, NormaBenito, José MiguelVallejo, AlejandroECRIS Network integrated in the Spanish AIDS Research NetworkBriz, VeronicaVázquez-Morón, SoniaFernández, AGarcía, PPernas, MariaCasado, ConcepcionLópez, CCapa, LauraPérez, MAlcamí, José2021-03-272021-03-272019-08J Microbiol Immunol Infect . 2019 Aug;52(4):667-671.http://hdl.handle.net/20.500.12105/12456Exosome-derived miR-21 was independently associated with CD4 T cell decline in HIV-1-infected elite controllers (OR 0.369, 95% CI 0.137-0.994, p = 0.049). Also, a negative correlation between miR-21 expression and MCP-1 level was found (r = -0.649, p = 0.020), while no correlation between soluble biomarkers or cellular immune activation was found.engVoRhttp://creativecommons.org/licenses/by-nc-nd/4.0/ExosomesmiRNAsHIV-1Elite controllersImmune activationSoluble biomarkersExosomesAdultBiomarkersCD4 Lymphocyte CountCD4-Positive T-LymphocytesChemokine CCL2Cross-Sectional StudiesFemaleHIV InfectionsHIV-1HumansMaleMicroRNAsMiddle AgedPlasmaLower expression of plasma-derived exosome miR-21 levels in HIV-1 elite controllers with decreasing CD4 T cell countAttribution-NonCommercial-NoDerivatives 4.0 Internacional30193823524667-67110.1016/j.jmii.2018.07.0071995-9133Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhiopen access