Caloto, Maria TeresaHuerta-Alvarez, ConsueloMoreno-Casbas, TeresaGuerra, DoloresAlcaide, JoséCastells, ConchaCardenal, José IDomínguez, AngelaGayoso-Diz, PilarGutiérrez, GonzaloLópez, Maria JMuñoz, FranciscoNavarro, CarmenPicó, MiguelPozo Sanchez, FranciscoQuirós, José RRobles, FranciscoSánchez, José MVanaclocha, HermelindaVega, TomásDiez Ruiz-Navarro, MercedesMulticentre Project for Tuberculosis Research Study Group2019-01-312019-01-312001-12-21BMC Med Res Methodol. 2001 Dec 21;1:14.http://hdl.handle.net/20.500.12105/7036Background: The Multicentre Project for Tuberculosis Research (MPTR) was a clinical-epidemiological study on tuberculosis carried out in Spain from 1996 to 1998. In total, 96 centres scattered all over the country participated in the project, 19935 "possible cases" of tuberculosis were examined and 10053 finally included. Data-handling and quality control procedures implemented in the MPTR are described. Methods: The study was divided in three phases: 1) preliminary phase, 2) field work 3) final phase. Quality control procedures during the three phases are described. Results: Preliminary phase: a) organisation of the research team; b) design of epidemiological tools; training of researchers. Field work: a) data collection; b) data computerisation; c) data transmission; d) data cleaning; e) quality control audits; f) confidentiality. Final phase: a) final data cleaning; b) final analysis. Conclusion: The undertaking of a multicentre project implies the need to work with a heterogeneous research team and yet at the same time attain a common goal by following a homogeneous methodology. This demands an additional effort on quality control.engVoRhttp://creativecommons.org/licenses/by-nd/4.0/ConfidentialityData CollectionData Interpretation, StatisticalHumansMulticenter Studies as TopicQuality ControlResearch DesignSpainTuberculosisAttribution-NoDerivatives 4.0 Internacional118606031141471-2288BMC medical research methodologyopen access