Titin mechanical unloading disrupts sarcomere tensional homeostasis triggering fast, non-canonical myocardial fibrosis

Lopez-Unzu MPricolo MRSilva-Rojas RVicente NGavilan-Herrera MVelazquez-Carreras DMorales-Lopez CHerrero-Galan, ElasAlegre-Cebollada, Jorge2024-06-262024-06-262024-05-29Cardiovasc Res. 2024; 120(1): cvae088.13http://hdl.handle.net/20.500.12105/19874engVoRhttp://creativecommons.org/licenses/by-nc-nd/4.0/AnimalsChromatography, Thin LayerDigitoxigeninDigitoxinHydroxylationIn Vitro TechniquesMaleMicrosomes, LiverNADPRatsTime FactorsTitin mechanical unloading disrupts sarcomere tensional homeostasis triggering fast, non-canonical myocardial fibrosisAttribution-NonCommercial-NoDerivatives 4.0 Internacional10.1093/cvr/cvae088.1381201cvae088.1310.1093/cvr/cvae088.1381755-3245CARDIOVASCULAR RESEARCHopen access