Codina Márquez, HelenaQuero-Delgado, MartaGómez, RafaelResino, SalvadorMartinez, IsidoroSepulveda-Crespo, Daniel2026-06-262026-06-262026-02-26Codina H, Quero-Delgado M, Gómez R, Resino S, Martínez I, Sepúlveda-Crespo D. Dengue nanosensors: a roadmap for clinical viability. Trends Biotechnol. 2026 Feb 26:S0167-7799(26)00005-3. doi: 10.1016/j.tibtech.2026.01.005. Epub ahead of print. PMID: 41760427.https://hdl.handle.net/20.500.12105/27568Dengue nanosensors promise much but have failed in clinical application. This paradox stems from a focus on record sensitivity over real-world robustness. We propose a paradigm shift from materials discovery to product engineering, providing a translational roadmap to guide viable diagnostics from the lab bench to the patient.engAMhttp://creativecommons.org/licenses/by-nc-nd/4.0/Clinical translationDengue virusNanosensorsPoint-of-care (PoC) diagnosticsSensor validationAttribution-NonCommercial-NoDerivatives 4.0 International4176042710.1016/j.tibtech.2026.01.005Trends in Biotechnologyembargoed access