Galmes-Panades, Aina MariaAngullo, EscarlataMira-Martínez, SofíaBennasar-Veny, MiquelZamanillo Campos, RocíoGomez-Juanes, RocíoKonieczna, JadwigaJiménez, RafaelSerrano-Ripoll, Maria JesusFiol-deRoque, Maria AntoniaMiralles, JerónimaYáñez, Aina MRomaguera, DoraVidal-Thomàs, María ClaraLlobera Cànaves, JoanGarcia Toro, MauroVicens-Caldentey, CaterinaGervilla Garcia, ElenaOña, José IvánMalih, NargesLeiva Rus, AlfonsoBulilete, OanaMontaño, Juan JoséGili, MargalidaRoca, MiquelRicci-Cabello, Ignacio2024-10-042024-10-042022-11-09Galmes-Panades AM, Angullo E, Mira-Martínez S, Bennasar-Veny M, Zamanillo-Campos R, Gómez-Juanes R, et al. Development and Evaluation of a Digital Health Intervention to Prevent Type 2 Diabetes in Primary Care: The PREDIABETEXT Study Protocol for a Randomised Clinical Trial. Int J Environ Res Public Health. 2022 Nov 9;19(22):14706.http://hdl.handle.net/20.500.13003/18612https://hdl.handle.net/20.500.12105/23413Background: Type 2 diabetes mellitus (T2DM) is a highly prevalent disease associated with an increased risk of comorbidities, premature death, and health costs. Prediabetes is a stage of glucose alteration previous to T2DM, that can be reversed. The aim of the study is to develop and evaluate a low-intensity, multifaceted, digital intervention to prevent T2DM. The intervention comprises: (1) the use of mobile health technology to send tailored text messages promoting lifestyle changes to people at risk of T2DM and (2) the provision of online education to primary healthcare physicians and nurses about management of prediabetes. Methods: In stages 1-4 we will design, develop and pilot-test the intervention. In Stage 5 we will conduct a phase II, six-month, three-arm, cluster randomized, clinical trial with 42 primary care professionals and 420 patients at risk of T2DM. Patients will be allocated to a control group (usual care), intervention A (patient messaging intervention), or intervention B (patient messaging intervention plus online education to their primary healthcare professionals). The primary outcome will be glycated haemoglobin. All the procedures obtained ethical approval in June 2021 (CEI-IB Ref No: IB4495/21PI). Discussion: Digital health interventions can effectively prevent T2DM and reduce important T2DM risk factors such as overweight or hypertension. In Spain, this type of intervention is understudied. Moreover, there is controversy regarding the type of digital health interventions that are more effective. Findings from this study may contribute to address T2DM prevention, through a low-cost and easily implementable intervention.enghttp://creativecommons.org/licenses/by/4.0/Diabetes Mellitus, Type 2Prediabetic StateRandomized Controlled Trials as TopicText MessagingHumansLife StylePrimary Health CareClinical Trials, Phase II as Topicresearch articleAttribution 4.0 International36429423192210.3390/ijerph1922147061660-4601International journal of environmental research and public healthopen accessEnsayos Clínicos Fase II como AsuntoHumanosEstado PrediabéticoEstilo de VidaDiabetes Mellitus Tipo 2Atención Primaria de SaludEnsayos Clínicos Controlados Aleatorios como AsuntoEnvío de Mensajes de Texto2-s2.0-85142634646887225100001L2020231821