Latasa, PelloDe Ory, Fernando deArribas, José RamónSánchez-Uriz, Maria ÁngelesSanchez-Arcilla, IgnacioOrdobás, MaríaNegredo, AnabelTrigo, ElenaDelgado, PilarMarzola, MarcoLopaz Pérez, María ÁngelesSánchez-Seco, María PazCalle-Prieto, Fernando de laFerrera, PilarRodríguez, ElenaMartin, AlejandroDel Cerro, Maria FelipaCórdoba, EstherMora-Rillo, MartaEsteban, Maria José2020-10-152020-10-152020-10J Infect Public Health. 2020 Oct;13(10):1595-1598.http://hdl.handle.net/20.500.12105/11171Crimean-Congo haemorrhagic fever (CCHF) is a widely distributed tick-borne disease. In Spain, the disease has emerged as outbreak associated with high-risk exposures. Our goal was to evaluate the prevalence of antibodies against the CCHF virus (CCHFV) in high-risk contacts. A cross-sectional study was conducted. Three hundred eighty-six high-risk contacts were identified comprising family contacts and hospital workers who had attended the cases. Fifty-seven cases with closer exposure were selected. However, forty-nine cases participated in the study. IgG antibodies were detected by immunoenzymatic techniques. All determinations tested negative for anti-CCHFV IgG antibodies. Most of the responders were women (73.5%), and belong to the intensive care department (53.1%). In relation to other possible sources of exposures, 18.4% travelled to countries with CCHF transmission risk. No CCHF positivity was recorded among selected high-risk contacts. This highlights the importance of standard precautions which might have protected healthcare workers and care providers from CCHF infection.engVoRhttp://creativecommons.org/licenses/by-nc-nd/4.0/Crimean-Congo haemorrhagic fever virusHealth surveillanceInfectious disease transmissionSerologyAttribution-NonCommercial-NoDerivatives 4.0 Internacional3282871513101595-159810.1016/j.jiph.2020.07.0161876-035XJournal of infection and public healthopen access