Pérez-Latorre, LeireBerenguer, JuanMicán, RafaelMontero, MartaCifuentes, CarmenPuig, TeresaSanz, JoséFerrero, Oscar Lde la Fuente, BelénRodríguez, CarmenReus, SergioHernández-Quero, JoséGaspar, GabrielPérez-Martínez, LauraGarcía, CoralForce, LuisVeloso, SergioDe Miguel, MartaJarrin Vera, InmaculadaGonzález-García, JuanGeSIDA 8514 Study Group2022-07-202022-07-202021-06Euro Surveill. 2021 Jun;26(25):2000236.http://hdl.handle.net/20.500.12105/14746Background: Recent and reliable estimates on the prevalence of coinfection with human immunodeficiency virus (HIV) and hepatitis B virus (HBV) in Europe are lacking.AimLeveraged on a study designed to assess HIV/HCV coinfection prevalence, we assessed the prevalence of HIV/HBV coinfection in Spain in 2018 and compared the results with five similar studies performed since 2002. Methods: This cross-sectional prevalence study was carried out in 43 centres, and patients were selected using simple random sampling. The reference population comprised 40,322 patients and the sample size were 1,690 patients.ResultsThe prevalence of HIV/HBV coinfection in Spain at the end of 2018 was 3.2%. The prevalence in 2002, 2009, 2015, 2016 and 2017 was 4.9%, 3.4%, 3%, 3.9% and 3%, respectively. Among the HIV/HBV-coinfected patients identified in 2018, 16.7% had cirrhosis according to transient elastography and 26.3% tested positive for antibodies against hepatitis D virus. All HIV/HBV-coinfected patients were receiving drugs with activity against HBV, and 97% of those tested for HBV DNA had an HBV DNA load < 80 IU/mL. Conclusions: The prevalence of HIV/HBV coinfection in Spain remained stable at around 3% for a decade. Our data could facilitate the design of national programmes to control HBV infection and help identify areas of patient management that need improvement.engVoRhttp://creativecommons.org/licenses/by/4.0/HBV therapyHIV/HBV coinfectionHepatitis delta virusCoinfectionHIV InfectionsHepatitis BCross-Sectional StudiesEuropeHepatitis B virusHumansPrevalenceSpainAtribución 4.0 Internacional341698182625200023610.2807/1560-7917.ES.2021.26.25.20002361560-7917Euro Surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletinopen access