Gómez-Aleza, CGonzález-Suárez, E2024-10-162024-10-162021-05-14Oncoimmunology . 2021 May 14;10(1):1923156.https://hdl.handle.net/20.500.12105/25173RANK signaling in mouse mammary tumor cells exerts an immunosuppressive environment by promoting the infiltration of pro-tumorigenic neutrophils and preventing CD8 T cell recruitment. Single-agent denosumab led to an increased tumor immune infiltration by lymphocytes and CD8 + T cells in breast cancer patients, supporting the immunomodulatory role of RANK signaling.engVoRhttp://creativecommons.org/licenses/by/4.0/RANKRANKLbreast cancerdenosumabimmunotherapyInhibition of RANK signaling as a potential immunotherapy in breast cancer.Attribution 4.0 International340263341011923156Oncoimmunologyopen access