González-Touya, MartaCarmona-Alferez, RocioSarria-Santamera, Antonio2022-04-192022-04-192021-07-12Healthcare (Basel). 2021;9(7):873.2227-9032http://hdl.handle.net/20.500.12105/14111Background: Diabetes mellitus is a significant public health problem. Macrovascular complications (stroke, acute myocardial infarction (AMI) and lower limb amputations (LLAs) represent the leading cause of morbi-mortality in DM. This work aims to evaluate the impact of the approval of the Diabetes Mellitus Strategy of the National Health System (SDM-NHS) on hospitalizations for those macrovascular complications related to DM. Methods: Interrupted time series applying segmented regression models (Negative Binomial) adjusted for seasonality to data from hospital discharge records with a primary or secondary diagnosis of DM (code 250 ICD9MC). Results: Between 2001 and 2015, there have been 7,302,750 hospital discharges with a primary or secondary diagnosis of DM. After the approval of the SDM-NHS, all the indicators showed a downward trend, modifying the previous trend in the indicators of AMI and LLA. The indicators of stroke and AMI also showed an immediate reduction in their rates. Conclusions: After the approval of the SDM-NHS, an improvement has been observed in all the indicators of macrovascular complications of DM evaluated, although it is difficult to establish a causal relationship between the strategy and the effects observed. Interrupted time series is applicable for evaluating the impact of interventions in public health when experimental designs are not possible.engVoRhttp://creativecommons.org/licenses/by/4.0/ComorbidityDiabetes mellitusHealth plan implementationInterrupted time seriesPredictive and preventive strategiesPublic policies evaluationAtribución 4.0 Internacional343562519787310.3390/healthcare9070873Healthcare (Basel, Switzerland)open access