López, J ABustos, ROrvell, CBerois, MArbiza, JGarcía-Barreno, BMelero, J A2025-01-292025-01-291998-08J Virol. 1998 Aug;72(8):6922-8.https://hdl.handle.net/20.500.12105/26195New series of escape mutants of human respiratory syncytial virus were prepared with monoclonal antibodies specific for the fusion (F) protein. Sequence changes selected in the escape mutants identified two new antigenic sites (V and VI) recognized by neutralizing antibodies and a group-specific site (I) in the F1 chain of the F molecule. The new epitopes, and previously identified antigenic sites, were incorporated into a refined prediction of secondary-structure motifs to generate a detailed antigenic map of the F glycoprotein.engVoRhttp://creativecommons.org/licenses/by-nc-nd/4.0/Attribution-NonCommercial-NoDerivatives 4.0 International965814772(8)6922-8Journal of Virologyopen access