Plaza, VicenteFernández-Rodríguez, ConcepciónMelero, CarlosGarcía-Cosío, BorjaManuel Entrenas, LuisPerez de Llano, Luis AlejandroGutierrez-Pereyra, FernandoTarragona, EduardPalomino, RosaLopez-Vina, AntolinTAI Study Grp2024-07-092024-07-092016-04-01Plaza V, Fernandez-Rodriguez C, Melero C, Cosio BG, Entrenas LM, Perez De Llano L, et al. Validation of the 'Test of the Adherence to Inhalers' (TAI) for Asthma and COPD Patients. J Aerosol Med Pulm Drug Deliv. 2016 Apr 01;29(2):142-52. Epub 2015 Jul 31.1941-2711http://hdl.handle.net/20.500.13003/17304http://hdl.handle.net/20.500.12105/20239Background: To validate the Test of Adherence to Inhalers' (TAI), a 12-item questionnaire designed to assess the adherence to inhalers in patients with COPD or asthma. Methods: A total of 1009 patients with asthma or COPD participated in a cross-sectional multicenter study. Patients with electronic adherence 80% were defined as adherents. Construct validity, internal validity, and criterion validity were evaluated. Self-reported adherence was compared with the Morisky-Green questionnaire. Results: Factor analysis study demonstrated two factors, factor 1 was coincident with TAI patient domain (items 1 to 10) and factor 2 with TAI health-care professional domain (items 11 and 12). The Cronbach's alpha was 0.860 and the test-retest reliability 0.883. TAI scores correlated with electronic adherence (=0.293, p=0.01). According to the best cut-off for 10 items (score 50, area under the ROC curve 0.7), 569 (62.5%) patients were classified as non-adherents. The non-adherence behavior pattern was: erratic 527 (57.9%), deliberate 375 (41.2%), and unwitting 242 (26.6%) patients. As compared to Morisky-Green test, TAI showed better psychometric properties. Conclusions: The TAI is a reliable and homogeneous questionnaire to identify easily non-adherence and to classify from a clinical perspective the barriers related to the use of inhalers in asthma and COPD.enghttp://creativecommons.org/licenses/by-nc/4.0/Anti-asthmatic agentsAdministration and dosageInhalersMedication adherenceMedication non-adherenceQuestionnairesPulmonary diseaseChronic obstructiveDrug therapyValidation studiesArea Under CurveAsthmaAgedSpainAdultPulmonary Disease, Chronic ObstructiveHumansHealth Knowledge, Attitudes, PracticeBronchodilator AgentsMiddle AgedCross-Sectional StudiesLungMaleresearch articleAttribution-NonCommercial 4.0 International26230150292142-45210.1089/jamp.2015.12121941-2703Journal of Aerosol Medicine and Pulmonary Drug Deliveryopen accessReproducibilidad de los ResultadosFemeninoPulmónAdministración por InhalaciónMasculinoNebulizadores y VaporizadoresCumplimiento de la MedicaciónEstudios TransversalesEnfermedad Pulmonar Obstructiva CrónicaBroncodilatadoresProyectos PilotoHumanosPersona de Mediana EdadConocimientos, Actitudes y Práctica en SaludAncianoAsmaEncuestas y CuestionariosAdultoPsicometríaEspañaÁrea Bajo la CurvaCurva ROC2-s2.0-84964762520373922800005L610199098