Mazagatos, ClaraMonge Corella, SusanaOlmedo, CarmenVega-Piris, LorenaGallego Berciano, PilarMartín-Merino, ElisaSierra, María JoséLimia, AuroraLarrauri, AmparoWorking group for the surveillance and control of COVID-19 in Spain2022-04-072022-04-072021Euro Surveill. 2021;26(24).http://hdl.handle.net/20.500.12105/13943Residents in long-term care facilities (LTCF) experienced a large morbidity and mortality during the COVID-19 pandemic in Spain and were prioritised for early COVID-19 vaccination. We used the screening method and population-based data sources to obtain estimates of mRNA COVID-19 vaccine effectiveness for elderly LTCF residents. The estimates were 71% (95% CI: 56-82%), 88% (95% CI: 75-95%), and 97% (95% CI: 92-99%), against SARS-CoV-2 infections (symptomatic and asymptomatic), and COVID-19 hospitalisations and deaths, respectively.engVoRhttp://creativecommons.org/licenses/by/4.0/COVID-19LTCFScreeningSurveillanceVaccinationCOVID-19COVID-19 VaccinesAgedHospitalizationHumansLong-Term CarePandemicsRNA, MessengerSARS-CoV-2SpainAtribución 4.0 Internacional34142647262410.2807/1560-7917.ES.2021.26.24.21004521560-7917Euro Surveillanceopen access