Lopez-Sainz, AngelaCliment, VicenteRipoll-Vera, TomásAngeles Espinosa, MariaBarriales-Villa, RobertoNavarro, MarinaLimeres, JavierDomingo, DianaKasper, David CGarcia-Pavia, Pablo2024-09-102024-09-102019-07-08Lopez-Sainz A, Climent V, Ripoll-Vera T, Espinosa MA, Barriales-Villa R, Navarro M, et al. D249 [letter]. Orphanet J Rare Dis. 2019 Jul 08;14.170.1750-1172http://hdl.handle.net/20.500.13003/15942https://hdl.handle.net/20.500.12105/22657Identification of Fabry disease (FD) in cardiac patients has been restricted so far to patients with left ventricular hypertrophy. Conduction problems are frequent in FD and could precede other manifestations, offering a possible earlier diagnosis.We studied the prevalence of FD in 188 patients <70years with conduction problems requiring pacemaker implantation. Although classical manifestations of FD were not rare, no patient with FD was identified. Screening efforts should not be conducted in this population.enghttp://creativecommons.org/licenses/by/4.0/Fabry diseaseConduction diseasePacemakerLeft ventricular hypertrophyScreeningAgedMalePacemaker, ArtificialMutationFemaleHumansCardiomyopathy, HypertrophicEchocardiographyFabry DiseaseMiddle Agedletter to the editorAttribution 4.0 International312869591417010.1186/s13023-019-1140-3Orphanet Journal of Rare Diseasesopen accessEcocardiografíaCardiomiopatía HipertróficaMarcapaso ArtificialHumanosPersona de Mediana EdadEnfermedad de FabryAncianoFemeninoMutaciónMasculino2-s2.0-85068870122475683800001L628451879