Vazquez-Moreno, Julio AlbertoMarcos-Moreno, Maria del CarmenBerron-Morato, Sonsoles2020-12-152020-12-151994-10Epidemiol Infect . 1994 Oct;113(2):267-74.http://hdl.handle.net/20.500.12105/11530To know the types of meningococcal strains in Spain, we serotyped and subtyped 743 Neisseria meningitidis isolates recovered between 1990 and 1992 from patients. A great number of serogroup B, serogroup C and non-groupable meningococci reacted with the serotyping reagents while many serogroup C and non-groupable isolates did not react with the serosubtyping reagents (78.2% and 54.8% respectively); only 8.9% of serogroup B meningococci were non-subtypeable (NST). Distribution of serotypes was similar in serogroup C and in non-groupable strains. Isolates showed great variability in antigenic phenotypes (71 in serogroup B, 20 in serogroup C and 25 in non-groupable meningococci). The most frequent antigenic combinations were 4:P1.15 (39.8%) in serogroup B, 2b:NST (55.8%) in serogroup C and 2b:NST (35.6%) in non-groupable meningococci.engVoRhttp://creativecommons.org/licenses/by-nc-nd/4.0/Disease OutbreaksHumansMeningococcal InfectionsNeisseria meningitidisSerotypingSpainAttribution-NonCommercial-NoDerivatives 4.0 Internacional79256651132267-7410.1017/s09502688000516941469-4409Epidemiology and Infectionopen access