Vindel, AnaTrincado, PilarGomez, EAparicio, PilarMartin de Nicolas, MBoquete Blanco, Maria TeresaSaez-Nieto, Juan Antonio2020-12-142020-12-141994-04Epidemiol Infect . 1994 Apr;112(2):299-306.http://hdl.handle.net/20.500.12105/11525In recent years, methicillin-resistant Staphylococcus aureus (MRSA) isolates in Spain have increased dramatically; in 1986 there were only 1.2% MRSA amongst all nosocomial Staphylococcus aureus (SA) isolates, by 1989 this percentage had risen to 44% in some hospital causing a very serious epidemic situation in the country. We have characterized these isolates by direct, reverse and Fisk phage typing and we have also looked for an additional local set of phages to help us to differentiate these strains. We have been able to differentiate an epidemic strain from other MRSA strains which cause sporadic hospital outbreaks, and we have also distinguished between some variants of the epidemic strain.engVoRhttp://creativecommons.org/licenses/by-nc-nd/4.0/Disease OutbreaksMethicillin ResistanceBacteriophage TypingCross InfectionHumansMicrobial Sensitivity TestsAttribution-NonCommercial-NoDerivatives 4.0 Internacional81500041122299-30610.1017/s095026880005771x1469-4409Epidemiology and Infectionopen access