2026-06-14T03:38:18Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/98162025-05-23T14:26:21Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Luz, Sérgio Luiz Bessa author Crainey, James Lee author Shelley, Anthony John author Rubio Muñoz, Jose Miguel author 2014-07 In a recent issue of Memórias do Instituto Oswaldo Cruz, published in Rio de Janeiro in February 2014 (109: 87-92), Adami et al. have published a survey reporting Mansonella parasite prevalence in the Amazon Region. This report makes a useful contribution to the existing knowledge of filarial parasite distribution within the Amazon area, parasite prevalence rates in relation to age and occupation and provides observations on the possible clinical impact of Mansonella ozzardi. Their publication also provides an account of what appears to be a novel ELISA that has recently been used in the Simuliidae and Onchocerciasis Laboratory of the Oswaldo Cruz Institute, Rio de Janeiro, Brazil. We are concerned that the publication of this ELISA may have created an excessively positive impression of the effectiveness of the onchocerciasis recrudescence serological surveillance tools that are presently available for use in the Amazonia onchocerciasis focus. In this letter we have, thus, sought to highlight some of the limitations of this ELISA and suggest how continuing insecurities concerning the detection of antibodies to Onchocerca volvulus within the Amazonia onchocerciasis focus might be minimised. Mem Inst Oswaldo Cruz. 2014 Jul;109(4):506-8. 10.1590/0074-0276140079 1678-8060 0074-0276 Memorias do Instituto Oswaldo Cruz 25075790 http://hdl.handle.net/20.500.12105/9816 Outstanding insecurities concerning the use of an Ov16-based ELISA in the Amazonia onchocerciasis focus