2026-06-14T03:54:53Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/95972024-10-21T08:05:12Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19608
Repisalud
author
Perez de Castro, Ignacio
author
Carmena, Mar
author
Prigent, Claude
author
Glover, David M
funder
Ministerio de Economía, Industria y Competitividad (España)
2020-04-17T09:24:25Z
2020-04-17T09:24:25Z
2017
Front Oncol. 2017 Mar 22;7:48.
10.3389/fonc.2017.00048
2234-943X
Frontiers in oncology
28382277
http://hdl.handle.net/20.500.12105/9597
Aurora kinases are key mitotic regulators that have also been associated with tumor development and progression. The interest on this highly conserved family of protein kinases has grown exponentially since they were discovered in the 1990s. Despite the steady increase in the number of laboratories involved and the consequent boost of the volume of research output during the last years, the study of Aurora kinases remains a very dynamic area in which new discoveries frequently keep coming to light. From a clinical perspective, the interest on Aurora kinase biology stems from their identification as targets for drug development; an increasing number of Aurora kinase inhibitors are being tested in preclinical projects and clinical trials. In this Frontiers Research Topic, we have aimed to not only review and revisit different aspects of the functions and regulation of Aurora kinases but also provide a forum for the publication of new developments in the field. We have been privileged to count on contributions from authors and reviewers that include some of the most experienced voices in our research area.
eng
Antitumoral therapy
Aurora inhibitors
Aurora kinase
Mitosis
Non-canonical roles
Editorial: Aurora Kinases: Classical Mitotic Roles, Non-Canonical Functions and Translational Views
editorial
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EditorialAuroraKinasesClassical_2017.pdf
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EditorialAuroraKinasesClassical_2017.pdf.txt