2026-06-14T03:40:56Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/95622025-06-04T07:46:32Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19609col_20.500.12105_16960

00925njm 22002777a 4500 dc Monsalve Arteaga, Lía author Muñoz Bellido, Juan Luis author Vieira Lista, María Carmen author Vicente Santiago, María Belén author Fernández Soto, Pedro author Bas, Isabel author Leralta, Nuria author De Ory, Fernando de author Negredo, Anabel author Sánchez-Seco, María Paz author Alonso Sardón, Montserrat author Pérez González, Sonia author Jiménez Del Bianco, Ana author Blanco Peris, Lydia author Alamo-Sanz, Rufino author Hewson, Roger author Belhassen-García, Moncef author Muro, Antonio author 2020-03 BackgroundCrimean-Congo haemorrhagic fever virus (CCHFV) is considered an emerging or even a probable re-emerging pathogen in southern Europe. Presence of this virus had been reported previously in Spain in 2010.AimWe aimed to evaluate the potential circulation of CCHFV in western Spain with a serosurvey in asymptomatic adults (blood donors).MethodsDuring 2017 and 2018, we conducted a CCHFV serosurvey in randomly selected asymptomatic blood donors from western Spain. Three assays using specific IgG antibodies against CCHFV were performed: the VectoCrimea ELISA test, an in-house ELISA and indirect immunofluorescence (EuroImmun) test with glycoprotein and nucleoprotein.ResultsA total of 516 blood donors participated in this cross-sectional study. The majority of the study participants were male (68.4%), and the mean age was 46.3 years. Most of the participants came from rural areas (86.8%) and 68.6% had contact with animals and 20.9% had animal husbandry practices. One in five participants (109/516, 21.1%) were engaged in at-risk professional activities such as agriculture and shepherding, slaughtering, hunting, veterinary and healthcare work (mainly nursing staff and laboratory technicians). A total of 15.3% of the participants were bitten by ticks in the days or months before the date of sampling. We detected anti-CCHFV IgG antibodies with two diagnostic assays in three of the 516 individuals and with one diagnostic assay in six of the 516 individuals.ConclusionSeroprevalence of CCHFV was between 0.58% and 1.16% in Castile-León, Spain. This is the first study in western Spain that showed circulation of CCHFV in healthy people. Euro Surveill. 2020 Mar;25(10). 10.2807/1560-7917.ES.2020.25.10.1900507 1560-7917 1560-7917 Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 32183933 http://hdl.handle.net/20.500.12105/9562 CCHF Crimean-Congo haemorrhagic fever Blood donor Emerging diseases Epidemiology Laboratory Re-emerging diseases Tick-borne diseases Viral haemorrhagic fever Crimean-Congo haemorrhagic fever (CCHF) virus-specific antibody detection in blood donors, Castile-León, Spain, summer 2017 and 2018