2026-06-14T03:32:02Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/91132024-09-27T21:54:44Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Velasco, María author Sánchez-Seco, María Paz author Campelo, Carolina author De Ory, Fernando de author Martin, Oriol author Herrero-Romero, Laura author Salmerón Béliz, Octavio J author Minguito, Teodora author Campos, Mª Carmen author Molero-Sanz, Francisca author Algora, Alejandro author Vazquez, Ana author 2020-01-29 We report the first human case of West Nile virus (WNV) lineage 2 infection imported to Spain by a traveler returning from Romania. Serum, cerebrospinal fluid and urine samples were analyzed and West Nile virus infection was identified by PCR and serological tests. The patient developed fever, diarrhea and neurological symptoms, accompanied by mild pancreatitis, described previously in very few cases as a complication of WNV infection and by alithiasic cholecystitis. Viral RNA was detected in urine until 30 days after the onset of symptoms and neutralizing antibodies were detected at very low titers. The phylogenetic analysis in a fragment of the NS5 gene of the virus showed a homology with sequences from WNV lineage 2 belonging to the monophyletic Central/Southern European group. Viruses. 2020 Jan 29;12(2). pii: E156. 10.3390/v12020156 1999-4915 1999-4915 Viruses 32013149 http://hdl.handle.net/20.500.12105/9113 Spain West Nile virus lineage 2 Digestive complications Human Neurological symptoms Imported Human West Nile Virus Lineage 2 Infection in Spain: Neurological and Gastrointestinal Complications