2026-04-27T03:43:09Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/90062024-09-27T22:07:47Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Chicharro, Carmen
author
Llanes-Acevedo, Ivonne Pamela
author
Garcia, Emilia
author
Nieto Martinez, Francisco Javier
author
Moreno, Javier
author
Cruz, Israel
funder
Instituto de Salud Carlos III
2020-02-03T08:59:09Z
2020-02-03T08:59:09Z
2013-07-25
Euro Surveill. 2013 Jul 25;18(30):20545.
http://hdl.handle.net/20.500.12105/9006
23929179
10.2807/1560-7917.es2013.18.30.20545
1560-7917
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Leishmaniasis is endemic in south-west Europe. Recent data point to the spread and (re-)emergence of this disease in previously endemic and non-endemic European countries. A recent example is the urban community outbreak of cutaneous and visceral leishmaniasis in the south-west of Madrid autonomous community, Spain, which began on 1 July 2009. A total of 446 cases associated to this outbreak were reported up to 31 December 2012. We show molecular typing data for 73 Leishmania infantum isolates obtained from January 2008 to July 2012 from different areas of Madrid, including those affected by the outbreak. Seven different genotypes were identified by combining data from two targets: the ribosomal internal transcribed spacers (ITS)-1 and -2 and the haspb (k26) gene. The results contribute to a better understanding of the parasite population circulating in the region, and indicate that most of the outbreak-associated isolates (22/31) were infected by parasites with the same combined genotype. Additional data from 82 L. infantum isolates typed as either MON-1 or MON-24 by isoenzyme analysis indicate that far from concluding that the outbreak was caused by a 'new' emerging genotype, further molecular typing-based surveillance studies are required to better understand the epidemiology of leishmaniasis in the region.
eng
Molecular typing of Leishmania infantum isolates from a leishmaniasis outbreak in Madrid, Spain, 2009 to 2012
journal article
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URL
https://repisalud.isciii.es/bitstreams/293be003-2149-4fa1-9264-3f03e73652ac/download
File
MD5
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application/pdf
MolecularTypingOfLeishmania_2013.pdf
URL
https://repisalud.isciii.es/bitstreams/d70229ab-f432-46f2-a21d-a9269b7e1814/download
File
MD5
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text/plain
MolecularTypingOfLeishmania_2013.pdf.txt