2026-04-27T08:01:53Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/89762024-09-27T07:57:33Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
de la Visitación, Néstor
author
Robles-Vera, Iñaki
author
Toral, Marta
author
Duarte, Juan
funder
Ministerio de Economía y Competitividad (España)
funder
Instituto de Salud Carlos III
funder
Centro de Investigación Biomedica en Red - CIBER
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
2020-01-29T11:49:11Z
2020-01-29T11:49:11Z
2019-11-05
Nutrients. 2019; 11(11):e2676
2072-6643
http://hdl.handle.net/20.500.12105/8976
31694260
10.3390/nu11112676
2072-6643
Nutrients
The prevalence of renal and cardiovascular disease (CVD) in patients with systemic lupus erythematosus (SLE) is higher than in general populations. Recently, a causal role of gut microbiota on the development of immune responses in SLE has been described. Probiotic consumption changes the composition of gut microbiota, preventing SLE progression. The aim of this review is to explore the role of the gut microbiota in the development of renal and cardiovascular disease in SLE and how probiotics could be a therapeutic option. Despite strong evidence on the beneficial effects of probiotics in the development of autoimmunity and nephritis in SLE, only a few studies described the protective effects of Lactobacillus in important risk factors for CVD, such as endothelial dysfunction and hypertension in mice. The preventive effects of probiotics in renal and CVD in humans have not been established yet.
eng
Endothelial dysfunction
Gut microbiota
Hypertension
Immune response
Nephritis
Protective Effects of Probiotic Consumption in Cardiovascular Disease in Systemic Lupus Erythematosus
journal article
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URL
https://repisalud.isciii.es/bitstreams/8453f8f1-57f7-4ff7-96a3-430a065fd348/download
File
MD5
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1264333
application/pdf
ProtectiveEffectsProbioticConsumption_2019.pdf
URL
https://repisalud.isciii.es/bitstreams/4087a56a-1e9c-4f64-893c-55b144d62d5f/download
File
MD5
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text/plain
ProtectiveEffectsProbioticConsumption_2019.pdf.txt