2026-06-14T10:38:30Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/89712025-05-23T10:27:45Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Amaro, Fatima
author
Sánchez-Seco, María Paz
author
Vazquez, Ana
author
Alves, Maria J
author
Zé-Zé, Líbia
author
Luz, Maria T
author
Minguito, Teodora
author
Fuente, Jesus de la
author
De Ory, Fernando de
funder
Instituto de Salud Carlos III
funder
Instituto de Salud Carlos III
2020-01-29T11:46:59Z
2020-01-29T11:46:59Z
2019
Viruses. 2019 Feb 20;11(2). pii: E179.
10.3390/v11020179
1999-4915
1999-4915
Viruses
30791664
http://hdl.handle.net/20.500.12105/8971
In the absence of viremia, the diagnostics of Zika virus (ZIKV) infections must rely on serological techniques. In order to improve the serological diagnosis of ZIKV, ZIKV-IgA and ZIKV-IgG avidity assays were evaluated. Forty patients returning from ZIKV endemic areas, with confirmed or suspected ZIKV infections were studied. Samples were classified as early acute, acute and late acute according to the number of days post illness onset. Low avidity IgG was only detected at acute and late acute stages and IgA mostly at the early acute and acute stages. The date of sampling provides useful information and can help to choose the best technique to use at a determined moment in time and to interpret low avidity IgG and IgA results, improving the serological diagnosis of ZIKV.
eng
IgA
IgG avidity tests
Zika virus
Cross-reactions
Dengue virus
Secondary infections
The Application and Interpretation of IgG Avidity and IgA ELISA Tests to Characterize Zika Virus Infections
research article
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URL
https://repisalud.isciii.es/bitstreams/e076ae2f-1819-4400-b47e-e89c9929acd1/download
File
MD5
a753f487472e2dd8a4e82613ccc2569f
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application/pdf
TheApplicationAndInterpretation_2019.pdf
URL
https://repisalud.isciii.es/bitstreams/679ef9f0-77f4-4943-bfe9-13a2bffa1306/download
File
MD5
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text/plain
TheApplicationAndInterpretation_2019.pdf.txt