2026-06-14T05:05:23Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/89712025-05-23T10:27:45Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609

00925njm 22002777a 4500 dc Amaro, Fatima author Sánchez-Seco, María Paz author Vazquez, Ana author Alves, Maria J author Zé-Zé, Líbia author Luz, Maria T author Minguito, Teodora author Fuente, Jesus de la author De Ory, Fernando de author 2019 In the absence of viremia, the diagnostics of Zika virus (ZIKV) infections must rely on serological techniques. In order to improve the serological diagnosis of ZIKV, ZIKV-IgA and ZIKV-IgG avidity assays were evaluated. Forty patients returning from ZIKV endemic areas, with confirmed or suspected ZIKV infections were studied. Samples were classified as early acute, acute and late acute according to the number of days post illness onset. Low avidity IgG was only detected at acute and late acute stages and IgA mostly at the early acute and acute stages. The date of sampling provides useful information and can help to choose the best technique to use at a determined moment in time and to interpret low avidity IgG and IgA results, improving the serological diagnosis of ZIKV. Viruses. 2019 Feb 20;11(2). pii: E179. 10.3390/v11020179 1999-4915 1999-4915 Viruses 30791664 http://hdl.handle.net/20.500.12105/8971 IgA IgG avidity tests Zika virus Cross-reactions Dengue virus Secondary infections The Application and Interpretation of IgG Avidity and IgA ELISA Tests to Characterize Zika Virus Infections