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oai:repisalud.isciii.es:20.500.12105/89372025-03-26T11:56:21Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19627

00925njm 22002777a 4500 dc Larsson, D G Joakim author Andremont, Antoine author Bengtsson-Palme, Johan author Koefoed Brandt, Kristian author de Roda Husman, Ana Maria author Fagerstedt, Patriq author Fick, Jerker author Flach, Carl-Fredrik author Gaze, William H author Kuroda, Makoto author Kvint, Kristian author Laxminarayan, Ramanan author Manaia, Celia M author Nielsen, Kaare Magne author Plant, Laura author Ploy, Marie-Cécile author Segovia, Jose Carlos author Simonet, Pascal author Smalla, Kornelia author Snape, Jason author Topp, Edward author van Hengel, Arjon J author Verner-Jeffreys, David W author Virta, Marko P J author Wellington, Elizabeth M author Wernersson, Ann-Sofie author 2018 There is growing understanding that the environment plays an important role both in the transmission of antibiotic resistant pathogens and in their evolution. Accordingly, researchers and stakeholders world-wide seek to further explore the mechanisms and drivers involved, quantify risks and identify suitable interventions. There is a clear value in establishing research needs and coordinating efforts within and across nations in order to best tackle this global challenge. At an international workshop in late September 2017, scientists from 14 countries with expertise on the environmental dimensions of antibiotic resistance gathered to define critical knowledge gaps. Four key areas were identified where research is urgently needed: 1) the relative contributions of different sources of antibiotics and antibiotic resistant bacteria into the environment; 2) the role of the environment, and particularly anthropogenic inputs, in the evolution of resistance; 3) the overall human and animal health impacts caused by exposure to environmental resistant bacteria; and 4) the efficacy and feasibility of different technological, social, economic and behavioral interventions to mitigate environmental antibiotic resistance.1. Environ Int. 2018 Aug;117:132-138. 10.1016/j.envint.2018.04.041 1873-6750 0160-4120 Environment international 29747082 http://hdl.handle.net/20.500.12105/8937 Antimicrobial resistance Environmental pollution Infectious diseases Risk assessment Risk management Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance