2026-07-21T21:47:38Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/85622025-05-27T12:27:18Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Yangzom, Thinley
author
Cruz, Israel
author
Bern, Caryn
author
Argaw, Daniel
author
den Boer, Margriet
author
Vélez, Iván Dario
author
Bhattacharya, Sujit K
author
Molina, Ricardo
author
Alvar, Jorge
funder
Agencia Española de Cooperación Internacional para el Desarrollo
2019-11-06T11:30:05Z
2019-11-06T11:30:05Z
2012-12
Am J Trop Med Hyg. 2012 Dec;87(6):1028-37. doi: 10.4269/ajtmh.2012.12-0211. Epub 2012 Oct 22.
10.4269/ajtmh.2012.12-0211
1476-1645
0002-9637
The American journal of tropical medicine and hygiene
23091191
http://hdl.handle.net/20.500.12105/8562
Visceral leishmaniasis was first reported in Bhutan in 2006. We conducted studies of the parasite, possible vectors and reservoirs, and leishmanin skin test and risk factor surveys in three villages. Nineteen cases were reported from seven districts. Parasite typing yielded two novel microsatellite sequences, both related to Indian L. donovani. In one case village, 40 (18.5%) of 216 participants had positive leishmanin skin test results, compared with 3 (4.2%) of 72 in the other case village and 0 of 108 in the control village. Positive results were strongly associated with the village and increasing age. None of the tested dogs were infected. Eighteen sand flies were collected, 13 Phlebotomus species and 5 Sergentomyia species; polymerase chain reaction for leishmanial DNA was negative. This assessment suggests that endemic visceral leishmaniasis transmission has occurred in diverse locations in Bhutan. Surveillance, case investigations, and further parasite, vector, and reservoir studies are needed. The potential protective impact of bed nets should be evaluated.
eng
Endemic transmission of visceral leishmaniasis in Bhutan
research article
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https://repisalud.isciii.es/bitstreams/3a036da5-a8b0-4622-bcb5-2a469f4008f6/download
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application/pdf
EndemicTransmissionOfVisceral_2012.pdf
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https://repisalud.isciii.es/bitstreams/cfafeb97-0db4-40d7-9f9f-5fe605e89665/download
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text/plain
EndemicTransmissionOfVisceral_2012.pdf.txt