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oai:repisalud.isciii.es:20.500.12105/83742024-09-27T09:49:21Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605

00925njm 22002777a 4500 dc del Fresno, Carlos author Cueto, Francisco J. author Sancho, David author 2019-09 Myeloid C-type lectin receptors (CLRs) comprise a family of receptors expressed by immune myeloid cells that share homologous C-type lectin domains. The implication of these CLRs in the regulation of homeostasis and activation of myeloid cells has generated a buoyant growth in the number of studies involving these receptors. Since their first description, diverse nomenclature has been used to refer to each of them, ranging from systematic classifications, such as gene name or cluster of differentiation, to non-systematic ones that include terminology based on gene expression patterns or function. In this review, we aim to summarize the different names used for the main myeloidCLRs and analyzewhich of themhave beenmore frequently used in the literature. In addition, we have examined the evolution of the terminology applied to these myeloid CLRs over time. Based on this analysis, we propose a consensus alias for each of those myeloid CLRs. However, we acknowledge that systematicity is required beyond this terminology based on use frequency. Therefore, we have included gene names as the standardization tool to gather the maximum agreement. We suggest that a standard nomenclature consisting of both gene names and consensus alias should be included at least in scientific abstracts, which would help to identify relevant literature, saving time and effort and fostering the research in this field in a more systematic manner. Front Immunol. 2019; 10:2098 10.3389/fimmu.2019.02098 1664-3224 Frontiers in Immunology http://hdl.handle.net/20.500.12105/8374 Lectin receptors Signaling Monocytes Macrophage Dentritic cells Innate immunity Nomenclature A Proposal for Nomenclature in Myeloid C-Type Lectin Receptors