2026-05-22T11:08:30Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/79952025-05-13T11:16:52Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Porta-Sanchez, Andreu
author
Magtibay, Karl
author
Nayyar, Sachin
author
Bhaskaran, Abhishek
author
Lai, Patrick F H
author
Massé, Stéphane
author
Labos, Christopher
author
Qiang, Beiping
author
Romagnuolo, Rocco
author
Masoudpour, Hassan
author
Biswas, Labonny
author
Ghugre, Nilesh
author
Laflamme, Michael
author
Deno, Don Curtis
author
Nanthakumar, Kumaraswamy
funder
Abbott
2019-07-30T09:08:58Z
2019-07-30T09:08:58Z
2019-02-04
Europace. 2019; 21(5):813-21
10.1093/europace/euy304
1532-2092
1099-5129
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
30726937
http://hdl.handle.net/20.500.12105/7995
Aims : Bipolar electrogram (BiEGM)-based substrate maps are heavily influenced by direction of a wavefront to the mapping bipole. In this study, we evaluate high-resolution, orientation-independent peak-to-peak voltage (Vpp) maps obtained with an equi-spaced electrode array and omnipolar EGMs (OTEGMs), measure its beat-to-beat consistency, and assess its ability to delineate diseased areas within the myocardium compared against traditional BiEGMs on two orientations: along (AL) and across (AC) array splines. Methods and results: The endocardium of the left ventricle of 10 pigs (three healthy and seven infarcted) were each mapped using an Advisor™ HD grid with a research EnSite Precision™ system. Cardiac magnetic resonance images with late gadolinium enhancement were registered with electroanatomical maps and were used for gross scar delineation. Over healthy areas, OTEGM Vpp values are larger than AL bipoles by 27% and AC bipoles by 26%, and over infarcted areas OTEGM Vpp values are 23% larger than AL bipoles and 27% larger than AC bipoles (P < 0.05). Omnipolar EGM voltage maps were 37% denser than BiEGM maps. In addition, OTEGM Vpp values are more consistent than bipolar Vpps showing less beat-by-beat variation than BiEGM by 39% and 47% over both infarcted and healthy areas, respectively (P < 0.01). Omnipolar EGM better delineate infarcted areas than traditional BiEGMs from both orientations. Conclusion: An equi-spaced electrode grid when combined with omnipolar methodology yielded the largest detectable bipolar-like voltage and is void of directional influences, providing reliable voltage assessment within infarcted and non-infarcted regions of the heart.
eng
Omnipolarity applied to equi-spaced electrode array for ventricular tachycardia substrate mapping
journal article
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