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oai:repisalud.isciii.es:20.500.12105/79482024-09-27T08:44:35Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605

00925njm 22002777a 4500 dc Andres-Manzano, Maria J. author Andres, Vicente author Dorado, Beatriz author 2015 Methods for staining tissues with Oil Red O and hematoxylin-eosin are classical histological techniques that are widely used to quantify atherosclerotic burden in mouse tissues because of their ease of use, reliability, and the large amount of information they provide. These stains can provide quantitative data about the impact of a genetic or environmental factor on atherosclerotic burden and on the initiation, progression, or regression of the disease, and can also be used to evaluate the efficacy of drugs designed to prevent or treat atherosclerosis. This chapter provides protocols for quantifying atherosclerotic burden in mouse aorta and aortic root, including methods for dissection, Oil Red O staining, hematoxylin-eosin staining, and image analysis. Methods Mol Biol. 2015; 1339:85-99 10.1007/978-1-4939-2929-0_5 1940-6029 978-1-4939-2929-0 1064-3745 Methods in molecular biology (Clifton, N.J.) 26445782 http://hdl.handle.net/20.500.12105/7948 Aorta Aortic root Atherosclerosis Dissection Hematoxylin-eosin Oil Red O Oil Red O and Hematoxylin and Eosin Staining for Quantification of Atherosclerosis Burden in Mouse Aorta and Aortic Root