2026-07-23T17:50:18Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/78532024-09-27T09:29:47Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Huertas, Jesus R.
author
Casuso, Rafael A.
author
Hernansanz-Agustín, Pablo
author
Cogliati, Sara
funder
Instituto de Salud Carlos III
funder
Ministerio de Ciencia, Innovación y Universidades (España)
funder
Fundación ProCNIC
2019-07-04T10:09:09Z
2019-07-04T10:09:09Z
2019-06
Oxid Med Cell Longev. 2019; 2019:7058350
10.1155/2019/7058350
1942-0900
Oxidative Medicine and Cellular Longevity
http://hdl.handle.net/20.500.12105/7853
Skeletal muscles require the proper production and distribution ofenergy to sustain their work. To ensure this requirement is met, mitochondria form large networks within skeletal muscle cells, and during exercise, they can enhance their functions. In the present review, we discuss recent findings on exercise-induced mitochondrial adaptations. We emphasize the importance ofmitochondrial biogenesis, morphological changes, and increases in respiratory supercomplex formation as mechanisms triggered by exercise that may increase the function of skeletal muscles. Finally, we highlight the possible effects of nutraceutical compounds on mitochondrial performance during exercise and outline the use of exercise as a therapeutic tool in noncommunicable disease prevention. The resulting picture shows that the modulation of mitochondrial activity by exercise is not only fundamental for physical performance but also a key point for whole-organism well-being.
eng
Stay Fit, Stay Young: Mitochondria in Movement: The Role of Exercise in the New Mitochondrial Paradigm
journal article
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URL
https://repisalud.isciii.es/bitstreams/be63fa62-765d-49d6-bf8b-82187b4a34b7/download
File
MD5
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application/pdf
StayFitStayYoung_2019.pdf
URL
https://repisalud.isciii.es/bitstreams/b1ac97d1-1139-4f7c-984f-eb39f5ba19e2/download
File
MD5
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text/plain
StayFitStayYoung_2019.pdf.txt