2026-04-29T15:25:26Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/78482024-09-27T10:15:32Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19607
Repisalud
author
Riobóo, Rafael J. Jiménez
author
Desco, Manuel
author
Gómez-Gaviro, María Victoria
funder
Ministerio de Ciencia, Innovación y Universidades (España)
funder
Fundación ProCNIC
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
funder
Comunidad de Madrid (España)
funder
Ministerio de Economía, Industria y Competitividad (España)
2019-07-03T14:03:54Z
2019-07-03T14:03:54Z
2019-06
Biomed Opt Express. 2019; 10(6):2674-2683
10.1364/BOE.10.002674
2156-7085
Biomedical Optics Express
31259043
http://hdl.handle.net/20.500.12105/7848
Brillouin spectroscopy is a well-established technology in condensed matter physics to characterize the mechanical properties of inert materials, and it has been extended very recently to the study of biological samples. Transparency is beneficial for samples to be properly analyzed by Brillouin spectroscopy. Here, we explored the efficacy of optical tissue clearing techniques to improve the acquisition of Brillouin spectra from biological tissues in order to analyze their biomechanical properties. We describe the first application of Brillouin scattering to optically cleared biological tissues with CUBIC protocol. We conclude that, within the range of error, tissue clearing does not modify the mechanical properties of the studied biological tissues.
eng
Impact of optical tissue clearing on the Brillouin signal from biological tissue samples
journal article
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URL
https://repisalud.isciii.es/bitstreams/5a5266fb-be7b-452c-9b77-4637ac0234bc/download
File
MD5
4030ec01997be9feba4299b7a43582c1
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application/pdf
ImpactOpticalTissueClearing_2019.pdf
URL
https://repisalud.isciii.es/bitstreams/2caa3dd8-eb23-4049-b09c-b13383fe5d9f/download
File
MD5
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text/plain
ImpactOpticalTissueClearing_2019.pdf.txt