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00925njm 22002777a 4500 dc Gonzalez Portal, Maria Eugenia author Carrasco, Luis author 2005 This chapter is devoted to reviewing some characteristics of membrane permeabilization by viral proteins. In addition, the methodology used to assay enhanced permeability in animal cells is described. Finally, the design of selective viral inhibitors based on the modification of cellular membranes during virus entry or at late times of infection is also discussed. González M.E., Carrasco L. (2005) Viral Proteins that Enhance Membrane Permeability. In: Fischer W.B. (eds) Viral Membrane Proteins: Structure, Function, and Drug Design. Protein Reviews, vol 1. Springer, Boston, MA 978-0-387-28146-9 978-0-306-48495-7 978-0-306-48495-7 http://hdl.handle.net/20.500.12105/7792 10.1007/0-387-28146-0_6 Protein Reviews, Vol I Viroporins Viral Glycoproteins Membrane permeabilization Antiviral agents Viroporin inhibitors Biological assays HIV-1 Poliovirus HIV-1 gp41 Viral Proteins that Enhance Membrane Permeability