2026-06-14T14:48:06Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/76012025-05-27T13:30:19Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Talavera, Sandra
author
Birnberg, Lotty
author
Nuñez, Ana I
author
Muñoz-Muñoz, Francesc
author
Vazquez, Ana
author
Busquets, Núria
funder
Ministerio de Economía y Competitividad (España)
2019-05-20T09:42:53Z
2019-05-20T09:42:53Z
2018
Parasit Vectors. 2018 May 23;11(1):310.
10.1186/s13071-018-2887-4
1756-3305
1756-3305
Parasites & vectors
29792223
http://hdl.handle.net/20.500.12105/7601
BACKGROUND: Rift Valley fever is a mosquito-borne zoonotic disease that affects domestic ruminants and humans. Culex flavivirus is an insect-specific flavivirus that naturally exists in field mosquito populations. The influence of Culex flavivirus on Rift Valley fever phlebovirus (RVFV) vector competence of Culex pipiens has not been investigated. METHODS: Culex flavivirus infection in a Cx. pipiens colony was studied by Culex flavivirus oral feeding and intrathoracical inoculation. Similarly, vector competence of Cx. pipiens infected with Culex flavivirus was evaluated for RVFV. Infection, dissemination, transmission rates and transmission efficiency of Culex flavivirus-infected and non-infected Cx. pipiens artificially fed with RVFV infected blood were assessed. RESULTS: Culex flavivirus was able to infect Cx. pipiens after intrathoracically inoculation in Cx. pipiens mosquitos but not after Culex flavivirus oral feeding. Culex flavivirus did not affect RVFV infection, dissemination and transmission in Cx. pipiens mosquitoes. RVFV could be detected from saliva of both the Culex flavivirus-positive and negative Cx. pipiens females without significant differences. Moreover, RVFV did not interfere with the Culex flavivirus infection in Cx. pipiens mosquitoes. CONCLUSIONS: Culex flavivirus infected and non-infected Cx. pipiens transmit RVFV. Culex flavivirus existing in field-collected Cx. pipiens populations does not affect their vector competence for RVFV. Culex flavivirus may not be an efficient tool for RVFV control in mosquitoes.
eng
Culex flavivirus
Culex pipiens
Rift Valley fever phlebovirus
Transmission
Vector competence
Culex flavivirus infection in a Culex pipiens mosquito colony and its effects on vector competence for Rift Valley fever phlebovirus
research article
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URL
https://repisalud.isciii.es/bitstreams/0b70f3f9-2577-4245-b5cc-eadfe918b227/download
File
MD5
2d0cb1fda319b374c8d955d621b6ac7a
815545
application/pdf
CulexFlavivirusInfectionIn_2018.pdf
URL
https://repisalud.isciii.es/bitstreams/4b62e83a-f469-4229-b932-61fcd1b89164/download
File
MD5
6b1550ca4021aa10fdc454270d1fabcb
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text/plain
CulexFlavivirusInfectionIn_2018.pdf.txt