2026-06-14T06:44:06Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/75362024-09-27T08:44:02Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Acin-Perez, Rebeca
author
Enriquez, Jose Antonio
funder
Ministerio de Ciencia e Innovación (España)
funder
Comunidad de Madrid (España)
funder
Unión Europea. Comisión Europea
funder
Ministerio de Economía y Competitividad (España)
funder
Fundación ProCNIC
2019-04-29T13:05:31Z
2019-04-29T13:05:31Z
2014-04
Biochim Biophys Acta. 2014; 1837(4):444-50
10.1016/j.bbabio.2013.12.009
0006-3002
Biochimica et biophysica acta
24368156
http://hdl.handle.net/20.500.12105/7536
Mitochondria are important organelles not only as efficient ATP generators but also in controlling and regulating many cellular processes. Mitochondria are dynamic compartments that rearrange under stress response and changes in food availability or oxygen concentrations. The mitochondrial electron transport chain parallels these rearrangements to achieve an optimum performance and therefore requires a plastic organization within the inner mitochondrial membrane. This consists in a balanced distribution between free respiratory complexes and supercomplexes. The mechanisms by which the distribution and organization of supercomplexes can be adjusted to the needs of the cells are still poorly understood. The aim of this review is to focus on the functional role of the respiratory supercomplexes and its relevance in physiology. This article is part of a Special Issue entitled: Dynamic and ultrastructure of bioenergetic membranes and their components.
eng
Metabolism
Mitochondrial supercomplex
OXPHOS
Respirasome
The function of the respiratory supercomplexes: the plasticity model
journal article
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URL
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application/pdf
TheFunctionRespiratorySupercomplexes_2014.pdf
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TheFunctionRespiratorySupercomplexes_2014.pdf.txt