2026-06-14T10:37:39Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/75292024-09-27T09:14:33Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Esser, Claudia
author
Bachmann, Anna
author
Kuhn, Daniela
author
Schuldt, Kathrin
author
Förster, Birgit
author
Thiel, Meike
author
May, Jürgen
author
Koch-Nolte, Friedrich
author
Yanez-Mo, Maria
author
Sanchez-Madrid, Francisco
author
Schinkel, Alfred H
author
Jalkanen, Sirpa
author
Craig, Alister G
author
Bruchhaus, Iris
author
Horstmann, Rolf D
2019-04-29T10:23:33Z
2019-04-29T10:23:33Z
2014-05
Cell Microbiol. 2014; 16(5):701-8
10.1111/cmi.12270
1462-5822
14625814
Cellular microbiology
24444337
http://hdl.handle.net/20.500.12105/7529
The adhesion of infected red blood cells (iRBCs) to human endothelium is considered a key event in the pathogenesis of cerebral malaria and other life-threatening complications caused by the most prevalent malaria parasite Plasmodium falciparum. In the past 30 years, 14 endothelial receptors for iRBCs have been identified. Exposing 10 additional surface proteins of endothelial cells to a mixture of P. falciparum isolates from three Ghanaian malaria patients, we identified seven new iRBC receptors, all expressed in brain vessels. This finding strongly suggests that endothelial binding of P. falciparum iRBCs is promiscuous and may use a combination of endothelial surface moieties.
eng
Evidence of promiscuous endothelial binding by Plasmodium falciparum-infected erythrocytes
journal article
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URL
https://repisalud.isciii.es/bitstreams/fe6246ff-d77b-443b-ac03-698d4c10c5a5/download
File
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EvidencePromiscuousEndothelialBinding _2014.pdf
URL
https://repisalud.isciii.es/bitstreams/a8427c70-e5c4-4fd7-928e-e3721e68dc6e/download
File
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text/plain
EvidencePromiscuousEndothelialBinding _2014.pdf.txt