2026-08-05T11:41:46Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/73702024-10-24T11:25:13Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19608
Repisalud
author
Lopez-Cima, Maria Felicitas
author
García-Pérez, Javier
author
Perez-Gomez, Beatriz
author
Aragones, Nuria
author
Lopez-Abente, Gonzalo
author
Tardón, Adonina
author
Pollan-Santamaria, Marina
funder
Instituto de Salud Carlos III
2019-03-26T11:59:52Z
2019-03-26T11:59:52Z
2011-01-25
Int J Health Geogr. 2011; 10:10
10.1186/1476-072X-10-10
1476-072X
International journal of health geographics
21266041
http://hdl.handle.net/20.500.12105/7370
BACKGROUND: Asturias, an Autonomous Region in Northern Spain with a large industrial area, registers high lung cancer incidence and mortality. While this excess risk of lung cancer might be partially attributable to smoking habit and occupational exposure, the role of industrial and urban pollution also needs to be assessed. The objective was to ascertain the possible effect of air pollution, both urban and industrial, on lung cancer risk in Asturias. METHODS: This was a hospital-based case-control study covering 626 lung cancer patients and 626 controls recruited in Asturias and matched by ethnicity, hospital, age, and sex. Distances from the respective participants' residential locations to industrial facilities and city centers were computed. Using logistic regression, odds ratios (ORs) and 95% confidence intervals (95%CIs) for categories of distance to urban and industrial pollution sources were calculated, with adjustment for sex, age, hospital area, tobacco consumption, family history of cancer, and occupation. RESULTS: Whereas individuals living near industries displayed an excess risk of lung cancer (OR = 1.49; 95%CI = 0.93-2.39), which attained statistical significance for small cell carcinomas (OR = 2.23; 95%CI = 1.01-4.92), residents in urban areas showed a statistically significant increased risk for adenocarcinoma (OR = 1.92; 95%CI = 1.09-3.38). In the Gijon health area, residents in the urban area registered a statistically significant increased risk of lung cancer (OR = 2.17; 95%CI = 1.25-3.76), whereas in the Aviles health area, no differences in risk were found by area of exposure. CONCLUSIONS: This study provides further evidence that air pollution is a moderate risk factor for lung cancer.
eng
Lung cancer risk and pollution in an industrial region of Northern Spain: a hospital-based case-control study
journal article
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LungCancerRiskAnd_2011.pdf
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https://repisalud.isciii.es/bitstreams/5fa22830-3618-4d0c-8862-2a9626a77ab1/download
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LungCancerRiskAnd_2011.pdf.txt