2026-06-14T06:44:08Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/73342024-09-27T20:19:51Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Parra, Mónica
author
Alcala, Adoración
author
Amoros, Cristina
author
Baeza, Anna
author
Galiana, Antonio
author
Tarrago Asensio, David
author
García-Quesada, Miguel Ángel
author
Sánchez-Hellín, Victoria
2019-03-14T12:14:37Z
2019-03-14T12:14:37Z
2017-05-25
Virol J. 2017 May;14(1):97.
10.1186/s12985-017-0764-y
1743-422X
Virology journal
28545483
http://hdl.handle.net/20.500.12105/7334
BACKGROUND: Primary Human herpesvirus-7 (HHV-7) infection usually occurs during childhood and causes several clinical manifestations: mainly exanthem subitum (roseola infantum), followed by a lifelong latent state with possible reactivation in case of immunodeficiency. Nevertheless, some considerably different approaches exist regarding the natural history of HHV-7 and the possible consequences of HHV-7 infection in immunocompetent adults. In particular, little is known about its pathogenic role in central nervous system (CNS) disease in nonimmunosuppressed adults. Specifically, in case of encephalitis, it is important to distinguish between infectious encephalitis and postinfectious encephalomyelitis for the management of patients CASE PRESENTATION: We describe here a case of encephalitis associated to human herpesvirus-7 with associated polymyeloradiculopathy in an immunocompetent patient which may contribute to the delineation of the approach to a patient profile with a similar clinical presentation and evolution to those presented in the literature. CONCLUSIONS: This case may alert clinicians to consider this specific etiology in the differential diagnosis of encephalopathy in patients with suspected infectious encephalitis who do not respond to acyclovir or in patients who develop acute polymyeloradiculopathy, considering that HHV-7 may be a pathological factor and that a timely diagnosis is crucial for the early administration of specific treatment.
eng
Clinical significance HHV-7 CNS infection
Human herpesvirus-7 encephalitis
Immunocompetent adults
Encephalitis associated with human herpesvirus-7 infection in an immunocompetent adult
journal article
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EncephalitisAssociatedWithHuman_2017.pdf.txt