2026-08-29T14:15:09Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/70782024-09-27T16:16:59Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19608col_20.500.12105_19609
Repisalud
author
Rábano, Alberto
author
Pedro-Cuesta, Jesus de
author
Mølbak, Kåre
author
Siden, Ake
author
Calero, Miguel
author
Laursen, Henning
author
EUROSURGYCJD Research Group
2019-02-04T09:49:54Z
2019-02-04T09:49:54Z
2005-01-24
BMC Public Health. 2005 Jan 24;5:9.
10.1186/1471-2458-5-9
1471-2458
BMC public health
15667663
http://hdl.handle.net/20.500.12105/7078
BACKGROUND: Epidemiological studies on the potential role of surgery in Creutzfeldt-Jakob Disease transmission have disclosed associations with history of specific surgical interventions or reported negative results. METHODS: Within the context of a case-control study designed to address surgical risk of sporadic Creutzfeldt-Jakob Disease in Nordic European countries (EUROSURGYCJD Project), a strategy was adopted to categorise reported surgical procedures in terms of potential risk of Creutzfeldt-Jakob Disease acquisition. We took into account elements of biological plausibility, either clinically or experimentally demonstrated, such as tissue infectivity, PrP expression content or successful route of infection. RESULTS: We propose a classification of exposed tissues and anatomic structures, drawn up on the basis of their specific putative role as entry site for prion transmission through contact with surgical instruments that are not fully decontaminated. CONCLUSIONS: This classification can serve as a reference, both in our study and in further epidemiological research, for categorisation of surgical procedures in terms of risk level of Creutzfeldt-Jakob Disease acquisition.
eng
Tissue classification for the epidemiological assessment of surgical transmission of sporadic Creutzfeldt-Jakob disease. A proposal on hypothetical risk levels
research article
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URL
https://repisalud.isciii.es/bitstreams/42e9e953-6490-46be-b0f8-524cb8cca258/download
File
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application/pdf
TissueClassificationForThe_2005.pdf
URL
https://repisalud.isciii.es/bitstreams/fa7107d7-1da6-4083-8733-a2d2c6e674b2/download
File
MD5
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text/plain
TissueClassificationForThe_2005.pdf.txt