2026-08-29T12:40:04Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/70712024-09-27T20:17:13Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Avellón, Ana
author
Casas Flecha, Inmaculada
author
Trallero, Gloria
author
Pérez, Carmen
author
Tenorio, Antonio
author
Palacios, Gustavo
funder
Instituto de Salud Carlos III
funder
National Institutes of Health (Estados Unidos)
2019-02-01T17:39:32Z
2019-02-01T17:39:32Z
2003-08
Emerg Infect Dis. 2003;9(8):934-41.
10.3201/eid0908.030080
1080-6040
Emerging infectious diseases
12967490
http://hdl.handle.net/20.500.12105/7071
Echovirus 13 (EV13), considered rare, was reported worldwide in 2000, mostly related to aseptic meningitis outbreaks. In Spain, 135 EV13 isolates were identified. The genetic relationships between 64 representative strains from Spain and other reported isolates from the United States, Germany, Italy, Japan, and Sweden were described by analyzing the partial sequence of the major capsid protein (VP1) gene. The strains from Spain were clearly identified as EV13 (79.5% similarity with the EV13 reference strain) and were grouped phylogenetically into two different clusters (by origination on either the Iberian Peninsula or Canary Islands). Isolates from Germany from 2000 clustered with the Canary Islands group. The isolates from other countries obtained before 2000 were genetically distant. Changes in EV13 coding sequence involved several differences in the C-terminal extreme of the VP1 protein. Part of the neutralizing antigenic site III has been described in this genome region in poliovirus and swine vesicular disease virus.
eng
Molecular analysis of echovirus 13 isolates and aseptic meningitis, Spain
journal article
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URL
https://repisalud.isciii.es/bitstreams/a151698a-fd2c-4d0d-922a-97337fbdd75c/download
File
MD5
e69bfb4eead50e52449c0970034850d2
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application/pdf
MolecularAnalysisOfEchovirus_2003.pdf
URL
https://repisalud.isciii.es/bitstreams/f298af72-16c8-41e3-83f4-b8c08f87c1ee/download
File
MD5
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text/plain
MolecularAnalysisOfEchovirus_2003.pdf.txt