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00925njm 22002777a 4500 dc García-Bujalance, Silvia author Navarro-San Francisco, Carolina author Rubio Muñoz, Jose Miguel author Arribas, José Ramón author Gutierrez, Avelino author 2012-04-27 As HIV becomes a chronic infection, an increasing number of HIV-infected patients are travelling to malaria-endemic areas. Association of malaria with HIV/AIDS can be clinically severe. Severe falciparum malaria is a medical emergency that is associated with a high mortality, even when treated in an Intensive Care Unit. This article describes two cases of HIV-positive patients, who returned from malaria-endemic areas and presented a parasitaemia > 5% of erythrocytes and clinical signs of severe falciparum malaria, both with > 350 CD4 cell count/μl, absence of chemoprophylaxis and successful response. Factors like drug interactions and the possible implication of anti-malarial therapy bioavailability are all especially interesting in HIV-malaria co-infections. Malar J. 2012 Apr 27;11:136. 10.1186/1475-2875-11-136 1475-2875 1475-2875 Malaria journal 22540214 http://hdl.handle.net/20.500.12105/6984 Imported Plasmodium falciparum malaria in HIV-infected patients: a report of two cases