2026-07-21T14:36:48Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/68922025-06-19T09:54:01Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19613

00925njm 22002777a 4500 dc Marventano, Stefano author Forjaz, Maria João author Grosso, Giuseppe author Mistretta, Antonio author Giorgianni, Gabriele author Platania, Alessio author Gangi, Santi author Basile, Francesco author Biondi, Antonio author 2013-10-08 BACKGROUND: Colorectal cancer (CRC) is the third most commonly diagnosed cancer in males and the second in females with a progressive increase in prevalence in industrialized countries. The loss of health due to the cancer and/or the consequence of the treatment may result in psychophysical, functional and social impairment; all of these affect health-related quality of life (QoL). DESCRIPTION: The most frequently CRC-specific QoL questionnaires is the FACT-C. QoL is not only important for the well-being of cancer patient but it also influences survival and response to therapy. Many studies investigated various determinants involved in the assessment of QoL in CRC, suggesting that symptoms, surgical procedures and the number of comorbidity significantly affected QoL. CONCLUSION: Despite that CRC patients have a relatively good QoL compared with the general population, a wide range of intervention could be undertaken to improve their QoL. The finding of this review may be useful for cancer clinicians in taking therapy and surveillance-related decisions. However, future research should be directed to large-scale prospective studies using well validated QoL instruments to facilitate comparison of results. BMC Surg. 2013;13 Suppl 2:S15. 10.1186/1471-2482-13-S2-S15 1471-2482 1471-2482 BMC surgery 24267735 http://hdl.handle.net/20.500.12105/6892 Health related quality of life in colorectal cancer patients: state of the art