2026-06-14T03:30:05Zhttps://repisalud.isciii.es/rest/oai/request

oai:repisalud.isciii.es:20.500.12105/68822025-06-19T07:55:42Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19613

00925njm 22002777a 4500 dc López-García-Franco, Alberto author del-Cura-González, María Isabel author Caballero-Martinez, Luis author Sanz-Cuesta, Teresa author Díaz-García, Marta Isabel author Rodríguez-Monje, María Teresa author Chahua Huarachi, Marcela author Muñoz-Sanchez, Inmaculada author Serrano-González, Dolores author Rollán-Llanderas, Teresa author Nieto-Blanco, Esther author Losada-Cucco, Liliana author Caballero-Martínez, Fernando author Sanz-García, Nuria author Pose-García, Belén author Jurado-Sueiro, Montserrat author Rey, Manuela Luque author García de Blas González, Francisca author Miguel Abanto, María Ángeles author Sanz Bayona, Teresa author Ayllón-Camargo, Rafaela author Santamaría López, Inmaculada author Santiago Hernando, María Luisa author Beltran-Alvarez, Rosario author Aguilar-Gutierrez, Ana Isabel author Mota-Rodriguez, Jose Luis author Cosculluela-Pueyo, Rafaél author López-Martín-Aragón, Teresa author Bonilla-Sanchez, Rosa author Aritieda-González-Granda, María del Carmen author Razola-Rincón, Raquel author Sánchez-de-la-Ventana, María Ángeles author Martinez-Guinea, Concepción author Huerta-Galindo, Luis author Barrio-Ovalle, Ana Belén author Miguel-Martín, Susana author Portero-Fraile, Paz author Pensado-Freire, Higinio author Herrera-García, María Luisa author Azcoaga-Lorenzo, Amaya author Gómez-García, Inés author Llamas-Sandino, Nuria author López-Borja, Isabel author Maldonado-Castro, Hortensia author Lumbreras-Villarán, Patricia author Ascanio-Durán, Carlos author 2012-05-02 BACKGROUND: Medically unexplained symptoms are an important mental health problem in primary care and generate a high cost in health services.Cognitive behavioral therapy and psychodynamic therapy have proven effective in these patients. However, there are few studies on the effectiveness of psychosocial interventions by primary health care. The project aims to determine whether a cognitive-behavioral group intervention in patients with medically unexplained symptoms, is more effective than routine clinical practice to improve the quality of life measured by the SF-12 questionary at 12 month. METHODS/DESIGN: This study involves a community based cluster randomized trial in primary healthcare centres in Madrid (Spain). The number of patients required is 242 (121 in each arm), all between 18 and 65 of age with medically unexplained symptoms that had seeked medical attention in primary care at least 10 times during the previous year. The main outcome variable is the quality of life measured by the SF-12 questionnaire on Mental Healthcare. Secondary outcome variables include number of consultations, number of drug (prescriptions) and number of days of sick leave together with other prognosis and descriptive variables. Main effectiveness will be analyzed by comparing the percentage of patients that improve at least 4 points on the SF-12 questionnaire between intervention and control groups at 12 months. All statistical tests will be performed with intention to treat. Logistic regression with random effects will be used to adjust for prognostic factors. Confounding factors or factors that might alter the effect recorded will be taken into account in this analysis. DISCUSSION: This study aims to provide more insight to address medically unexplained symptoms, highly prevalent in primary care, from a quantitative methodology. It involves intervention group conducted by previously trained nursing staff to diminish the progression to the chronicity of the symptoms, improve quality of life, and reduce frequency of medical consultations. TRIAL REGISTRATION: The trial was registered with ClinicalTrials.gov, number NCT01484223 [http://ClinicalTrials.gov]. BMC Fam Pract. 2012 May 2;13:35. 10.1186/1471-2296-13-35 1471-2296 1471-2296 BMC family practice 22551252 http://hdl.handle.net/20.500.12105/6882 Effectiveness of a cognitive behavioral intervention in patients with medically unexplained symptoms: cluster randomized trial