2026-07-21T13:56:06Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/68642024-09-27T09:50:30Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Li, Jackson LiangYao
author
Zarbock, Alexander
author
Hidalgo, Andres
funder
Deutsche Forschungsgemeinschaft (Alemania)
funder
Ministerio de Ciencia, Innovación y Universidades (España)
funder
Fundación ProCNIC
funder
Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF)
2018-12-17T11:29:40Z
2018-12-17T11:29:40Z
2017-07-18
J Exp Med. 2017; 214(8):2193
10.1084/jem.20170879
1540-9538
0022-1007
The Journal of experimental medicine
28720569
http://hdl.handle.net/20.500.12105/6864
Platelets participate in many important physiological processes, including hemostasis and immunity. However, despite their broad participation in these evolutionarily critical roles, the anucleate platelet is uniquely mammalian. In contrast with the large nucleated equivalents in lower vertebrates, we find that the design template for the evolutionary specialization of platelets shares remarkable similarities with human-engineered unmanned aerial vehicles in terms of overall autonomy, maneuverability, and expendability. Here, we review evidence illustrating how platelets are uniquely suited for surveillance and the manner in which they consequently provide various types of support to other cell types.
eng
Platelets as autonomous drones for hemostatic and immune surveillance
journal article
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URL
https://repisalud.isciii.es/bitstreams/20284512-301c-4d59-9d78-9a172083180f/download
File
MD5
cfbc1943475de3439a19ecba60346f9f
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application/pdf
PlateletsAsAutonomousDrones_2017.pdf
URL
https://repisalud.isciii.es/bitstreams/e230c5af-1c1d-4d95-a51e-bd0b676c44a2/download
File
MD5
1e8cf22909517ce1abb8d1c0120c858c
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text/plain
PlateletsAsAutonomousDrones_2017.pdf.txt