2026-06-14T05:06:00Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/67882024-09-27T21:02:55Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19609
Repisalud
author
Franco, Leticia
author
Palacios, Gustavo
author
Martinez, José Antonio
author
Vazquez, Ana
author
Savji, Nazir
author
De Ory, Fernando de
author
Sánchez-Seco, María Paz
author
Martín, Dolores
author
Lipkin, W Ian
author
Tenorio, Antonio
funder
Instituto de Salud Carlos III
2018-12-07T13:22:36Z
2018-12-07T13:22:36Z
2011-08-02
PLoS Negl Trop Dis. 2011 Aug;5(8):e1251.
10.1371/journal.pntd.0001251
1935-2735
1935-2735
PLoS neglected tropical diseases
21829739
http://hdl.handle.net/20.500.12105/6788
Dengue virus (DENV) circulates in human and sylvatic cycles. Sylvatic strains are both ecologically and evolutionarily distinct from endemic viruses. Although sylvatic dengue cycles occur in West African countries and Malaysia, only a few cases of mild human disease caused by sylvatic strains and one single case of dengue hemorrhagic fever in Malaysia have been reported. Here we report a case of dengue hemorrhagic fever (DHF) with thrombocytopenia (13000/µl), a raised hematocrit (32% above baseline) and mucosal bleeding in a 27-year-old male returning to Spain in November 2009 after visiting his home country Guinea Bissau. Sylvatic DENV-2 West African lineage was isolated from blood and sera. This is the first case of DHF associated with sylvatic DENV-2 in Africa and the second case worldwide of DHF caused by a sylvatic strain.
eng
First report of sylvatic DENV-2-associated dengue hemorrhagic fever in West Africa
journal article
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URL
https://repisalud.isciii.es/bitstreams/c8f6e783-738b-4c3f-8405-e3d99a42b250/download
File
MD5
0045f9b533265e84cf78827a2150a9dc
1123641
application/pdf
FirstReportofSylvatic_2011.pdf
URL
https://repisalud.isciii.es/bitstreams/9ccf4c2c-9e34-4b21-820c-a7eaa5a1771b/download
File
MD5
05043ef6027b652ad4ab1c5c77a0faa1
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text/plain
FirstReportofSylvatic_2011.pdf.txt