2026-04-29T07:21:36Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/67792025-05-08T15:38:56Zcom_20.500.12105_2052com_20.500.12105_2051col_20.500.12105_19611
Repisalud
author
Moreno, Marta
author
Salgueiro, Patrícia
author
Vicente, José Luis
author
Ochando, Jordi
author
Berzosa, Pedro
author
de Lucio, Aida
author
Simard, Frédéric
author
Caccone, Adalgisa
author
do Rosário, Virgílio E
author
Pinto, João
author
Benito, Agustin
funder
RETICS-Investigación colaborativa en Enfermedades Tropicales (RICET-ISCIII) (España)
funder
Agencia Española de Cooperación Internacional para el Desarrollo
funder
UNICEF - Fondo de las Naciones Unidas para la Infancia
funder
World Health Organization (WHO/OMS)
funder
World Bank Group
funder
United Nations Development Programme
2018-12-07T10:12:51Z
2018-12-07T10:12:51Z
2007-10-15
Malar J. 2007; 6: 137.
1475-2875
http://hdl.handle.net/20.500.12105/6779
17937805
10.1186/1475-2875-6-137
1475-2875
Malaria journal
BACKGROUND: Patterns of genetic structure among mosquito vector populations in islands have received particular attention as these are considered potentially suitable sites for experimental trials on transgenic-based malaria control strategies. In this study, levels of genetic differentiation have been estimated between populations of Anopheles gambiae s.s. from the islands of Bioko and Annobón, and from continental Equatorial Guinea (EG) and Gabon. METHODS: Genotyping of 11 microsatellite loci located in chromosome 3 was performed in three island samples (two in Bioko and one in Annobón) and three mainland samples (two in EG and one in Gabon). Four samples belonged to the M molecular form and two to the S-form. Microsatellite data was used to estimate genetic diversity parameters, perform demographic equilibrium tests and analyse population differentiation. RESULTS: High levels of genetic differentiation were found between the more geographically remote island of Annobón and the continent, contrasting with the shallow differentiation between Bioko island, closest to mainland, and continental localities. In Bioko, differentiation between M and S forms was higher than that observed between island and mainland samples of the same molecular form. CONCLUSION: The observed patterns of population structure seem to be governed by the presence of both physical (the ocean) and biological (the M-S form discontinuity) barriers to gene flow. The significant degree of genetic isolation between M and S forms detected by microsatellite loci located outside the "genomic islands" of speciation identified in A. gambiae s.s. further supports the hypothesis of on-going incipient speciation within this species. The implications of these findings regarding vector control strategies are discussed.
eng
Genetic population structure of Anopheles gambiae in Equatorial Guinea
research article
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https://repisalud.isciii.es/bitstreams/eceb9b44-745d-470b-ad6e-87ea43a066d7/download
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GeneticPopulationStructureOf_2007.pdf
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https://repisalud.isciii.es/bitstreams/1b37a153-8cac-4f82-8386-88dc8fa18fd4/download
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text/plain
GeneticPopulationStructureOf_2007.pdf.txt