2026-08-05T15:42:35Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/65422024-09-27T08:39:28Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud
author
Fernandez-Barahona, Irene
author
Munoz-Hernando, Maria
author
Pellico, Juan
author
Ruiz-Cabello, Jesus
author
Herranz, Fernando
funder
Ministerio de Economía, Industria y Competitividad (España)
funder
Instituto de Salud Carlos III
2018-10-26T07:59:27Z
2018-10-26T07:59:27Z
2018
Appl Sci. 2018; 8(7):1098
10.3390/app8071098
2076-3417
Applied Sciences
http://hdl.handle.net/20.500.12105/6542
The combination of radioisotopes and nanomaterials is creating a new library of tracers for molecular imaging, exploiting the sensitivity of nuclear imaging techniques and the size-dependent properties of nanomaterials. This new approach is expanding the range of applications, including the possibility of theranostics. Among the many different combinations, the use of Ga-68 as the radioisotope in the radio-nanomaterial is particularly convenient. The physicochemical properties of this isotope allow incorporating it into many materials with great chemical flexibility. Furthermore, its production from a benchtop generator eases the preparation of the tracer. Here, we review main results from the last years in which a nanomaterial has been radiolabeled with Ga-68. In thus process, we pay attention to the use of nanomaterials for biomedical imaging in general and main properties of this radioisotope. We study the main methods to carry out such radiolabeling and the most important applications for molecular imaging.
eng
Gallium-68
Radio-nanomaterials
Molecular imaging
Biomedical imaging
Nanoparticles
Radiochemistry
Nanomedicine
IRON-OXIDE NANOPARTICLES
POSITRON-EMISSION-TOMOGRAPHY
UP-CONVERSION NANOPARTICLES
SEMICONDUCTOR QUANTUM DOTS
SOMATOSTATIN RECEPTOR EXPRESSION
BRAIN-BARRIER PERMEABILITY
HUMAN-SERUM-ALBUMIN
IN-VIVO EVALUATION
DRUG-DELIVERY
MAGNETIC-RESONANCE
Molecular Imaging with Ga-68 Radio-Nanomaterials: Shedding Light on Nanoparticles
journal article
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MolecularImagingwith68Ga_2018.pdf
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05d6c14db2bd10fea5d807c4b6b0ffed
119851
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MolecularImagingwith68Ga_2018.pdf.txt