2026-04-29T15:25:26Zhttps://repisalud.isciii.es/rest/oai/request
oai:repisalud.isciii.es:20.500.12105/65162024-09-27T09:24:55Zcom_20.500.12105_19604com_20.500.12105_2051col_20.500.12105_19605
Repisalud author Halcox, Julian P. J. author Roy, Carine author Tubach, Florence author Banegas, José Ramón author Dallongeville, Jean author De Backer, Guy author Guallar, Eliseo author Sazova, Oguen author Medina, Jesus author Perk, Joep author Steg, Philippe Gabriel author Rodríguez-Artalejo, Fernando author Borghi, Claudio funder Oxford PharmaGenesis 2018-10-25T08:19:45Z 2018-10-25T08:19:45Z 2014 BMC Cardiovasc Disord. 2014; 14(1):25 10.1186/1471-2261-14-25 1471-2261 BMC Cardiovascular Disorders 24564178 http://hdl.handle.net/20.500.12105/6516 Background: Elevated C-reactive protein (CRP) levels are associated with high cardiovascular risk, and might identify patients who could benefit from more carefully adapted risk factor management. We have assessed the prevalence of elevated CRP levels in patients with one or more traditional cardiovascular risk factors. Methods: Data were analysed from the European Study on Cardiovascular Risk Prevention and Management in Usual Daily Practice (EURIKA, ClinicalTrials. gov Identifier: NCT00882336), which included patients (aged = 50 years) from 12 European countries with at least one traditional cardiovascular risk factor but no history of cardiovascular disease. Analysis was also carried out on the subset of patients without diabetes mellitus who were not receiving statin therapy. Results: In the overall population, CRP levels were positively correlated with body mass index and glycated haemoglobin levels, and were negatively correlated with high- density lipoprotein cholesterol levels. CRP levels were also higher in women, those at higher traditionally estimated cardiovascular risk and those with greater numbers of metabolic syndrome markers. Among patients without diabetes mellitus who were not receiving statin therapy, approximately 30\% had CRP levels >= 3 mg/ L, and approximately 50\% had CRP levels = 2 mg/ L, including those at intermediate levels of traditionally estimated cardiovascular risk. Conclusions: CRP levels are elevated in a large proportion of patients with at least one cardiovascular risk factor, without diabetes mellitus who are not receiving statin therapy, suggesting a higher level of cardiovascular risk than predicted according to conventional risk estimation systems. eng C-reactive protein Cardiovascular disease Epidemiology Risk factors/global assessment CORONARY-HEART-DISEASE PRIMARY PREVENTION CLINICAL-PRACTICE HEALTHY-ADULTS PREDICTION WOMEN INFLAMMATION POPULATION MORTALITY JUPITER C-reactive protein levels in patients at cardiovascular risk: EURIKA study journal article URL https://repisalud.isciii.es/bitstreams/4b2fe05b-db9f-4801-bd85-6d9da16ca03a/download File MD5 f0b2832469a3fc5ae47b87e5bb3cc817 418030 application/pdf C-reactiveProteinLevels_2014.pdf URL https://repisalud.isciii.es/bitstreams/37efc4b6-4423-41e9-9167-87e878ef3cf3/download File MD5 ac3ae6301da102f444cdeef1ce8147f0 168703 application/pdf C-reactiveProteinLevels_2014_MOESM1_ESM.pdf URL https://repisalud.isciii.es/bitstreams/7530294a-4969-4842-8ceb-d17316daf634/download File MD5 fab7570b5c0441e26fa82784361504f9 161601 application/pdf C-reactiveProteinLevels_2014__MOESM2_ESM.pdf URL https://repisalud.isciii.es/bitstreams/e5dd6cff-006b-4f99-b267-1d9746e6dca7/download File MD5 b101e6cc460d881c6a344f3c247f80c9 172488 application/pdf C-reactiveProteinLevels_2014_MOESM3_ESM.pdf URL https://repisalud.isciii.es/bitstreams/6bedc14a-be43-449b-b76c-03aa6ac626e7/download File MD5 a80c3acc4cd7f0a6d117ffc0f33ec324 70824 application/pdf C-reactiveProteinLevels_2014_MOESM4_ESM.pdf URL https://repisalud.isciii.es/bitstreams/3243428c-64e1-4f7f-b282-242fce803a63/download File MD5 82e4d24f487e74f95508d5af4a00452f 75246 application/pdf C-reactiveProteinLevels_2014_MOESM5_ESM.pdf URL https://repisalud.isciii.es/bitstreams/6456a10e-9d96-45b6-9e79-b17328e1aa09/download File MD5 2e2baccbedad39f2679b6513999ec203 77556 application/pdf C-reactiveProteinLevels_2014_MOESM6_ESM.pdf URL https://repisalud.isciii.es/bitstreams/aad9d435-ae82-47f7-9e4f-1b2765ee5060/download File MD5 5ccf4943d597f6f32ca07376fae2b370 47737 text/plain C-reactiveProteinLevels_2014.pdf.txt URL https://repisalud.isciii.es/bitstreams/7e4834e7-7c18-4873-b2f0-ca3f1a2d17e0/download File MD5 be7e0c2fbffb7c656e5b06924cebe4db 554 text/plain C-reactiveProteinLevels_2014_MOESM1_ESM.pdf.txt URL https://repisalud.isciii.es/bitstreams/6befe74d-917f-4165-9307-4795471491d9/download File MD5 18ce7a03f919ceb0246c1b523ca493ea 391 text/plain C-reactiveProteinLevels_2014__MOESM2_ESM.pdf.txt URL https://repisalud.isciii.es/bitstreams/5bbf4560-cebe-4989-9cb3-54261aab5e01/download File MD5 e8dc5b041e287e1aaaef941b8284c0b3 829 text/plain C-reactiveProteinLevels_2014_MOESM3_ESM.pdf.txt URL https://repisalud.isciii.es/bitstreams/9c51a0a5-bc5b-4ec0-a85a-69b38557bc81/download File MD5 fcf3ba52eb38478b3b84a9c746525ada 361 text/plain C-reactiveProteinLevels_2014_MOESM4_ESM.pdf.txt URL https://repisalud.isciii.es/bitstreams/b9ac649f-a089-4510-a5a0-8c91923a5138/download File MD5 3533715b4af677cc830a6c815a6e8acf 295 text/plain C-reactiveProteinLevels_2014_MOESM5_ESM.pdf.txt URL https://repisalud.isciii.es/bitstreams/fb1e9ef1-1426-4e0c-bdb6-fe104697362d/download File MD5 59cdc56503ddf38026cde97b5c0be72c 489 text/plain C-reactiveProteinLevels_2014_MOESM6_ESM.pdf.txt