2026-04-26T23:29:42Zhttps://repisalud.isciii.es/rest/oai/requestoai:repisalud.isciii.es:20.500.12105/57932024-11-28T16:47:40Zcom_20.500.12105_2052com_20.500.12105_2051com_20.500.12105_15322col_20.500.12105_19608col_20.500.12105_16958col_20.500.12105_16961col_20.500.12105_16972
Repisalud
author
Luquin, Maria-Rosario
author
Kulisevsky, Jaime
author
Martínez-Martín, Pablo
author
Mir, Pablo
author
Tolosa, Eduardo S.
2018-03-27T09:53:44Z
2018-03-27T09:53:44Z
2017-01-23
Parkinsons Dis. 2017; 2017:4047392
2090-8083
http://hdl.handle.net/20.500.12105/5793
28239501
10.1155/2017/4047392
2042-0080
Parkinson's Disease
To date, no consensus exists on the key factors for diagnosing advanced Parkinson disease (APD). To obtain consensus on the definition of APD, we performed a prospective, multicenter, Spanish nationwide, 3-round Delphi study (CEPA study). An ad hoc questionnaire was designed with 33 questions concerning the relevance of several clinical features for APD diagnosis. In the first-round, 240 neurologists of the Spanish Movement Disorders Group participated in the study. The results obtained were incorporated into the questionnaire and both, results and questionnaire, were sent out to and fulfilled by 26 experts in Movement Disorders. Review of results from the second-round led to a classification of symptoms as indicative of "definitive," "probable," and "possible" APD. This classification was confirmed by 149 previous participating neurologists in a third-round, where 92% completely or very much agreed with the classification. Definitive symptoms of APD included disability requiring help for the activities of daily living, presence of motor fluctuations with limitations to perform basic activities of daily living without help, severe dysphagia, recurrent falls, and dementia. These results will help neurologists to identify some key factors in APD diagnosis, thus allowing users to categorize the patients for a homogeneous recognition of this condition.
eng
Consensus on the Definition of Advanced Parkinson’s Disease: A Neurologists-Based Delphi Study (CEPA Study)
journal article
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URL
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ConsensusOnTheDefinition_2017.pdf
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ConsensusOnTheDefinition_2017.pdf.txt
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ConsensusOnTheDefinition_2017.pdf.txt
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ConsensusOnTheDefinition_2017.pdf.txt
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https://repisalud.isciii.es/bitstreams/7ed2bf03-e1c7-4295-b050-1775c65191e7/download
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ConsensusOnTheDefinition_2017.pdf.txt